This course introduces students to the pathophysiology of disease and illness across biological systems, emphasizing a holistic understanding of physiological responses and diagnostic processes. Students will apply clinical judgment and the nursing process to analyze health alterations and develop evidence-informed care strategies. Focus is placed on recognizing the impact of social determinants of health and promoting equitable, person-centered care. Prerequisites: BIOL 114, CHEM 106 or 121, BIOL 296 (or concurrent), admission to professional nursing sequence.